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1

Gazing into the future: Parkinson's disease gene therapeutics to modify natural history

Kathleen A. Maguire-Zeiss, Timothy R. Mhyre, Howard J. Federoff

Journal:

Experimental Neurology

Year:

2008

Language:

english

File:

PDF, 633 KB

english, 2008

2

Reduced expression of preproenkephalin in striatal neurons from huntington's disease patients

Dr Eric K. Richfield, Kathleen A. Maguire-Zeiss, Christopher Cox, Jennifer Gilmore, Pieter Voorn

Journal:

Annals of Neurology

Year:

1995

Language:

english

File:

PDF, 942 KB

english, 1995

3

Preferential loss of preproenkephalin versus preprotachykinin neurons from the striatum of Huntington's disease patients

Dr Eric K. Richfield, Kathleen A. Maguire-Zeiss, Harald E. Vonkeman, Pieter Voorn

Journal:

Annals of Neurology

Year:

1995

Language:

english

File:

PDF, 1.94 MB

english, 1995

4

Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model

Preeti J Khandelwal, Sonya B Dumanis, Li Rebekah Feng, Kathleen Maguire-Zeiss, GW Rebeck, Hilal A Lashuel, Charbel EH Moussa

Journal:

Molecular Neurodegeneration

Year:

2010

Language:

english

File:

PDF, 7.54 MB

english, 2010

5

Future directions for immune modulation in neurodegenerative disorders: focus on Parkinson’s disease

Kathleen A. Maguire-Zeiss, Howard J. Federoff

Journal:

Journal of Neural Transmission

Year:

2010

Language:

english

File:

PDF, 277 KB

english, 2010

6

Immune-Directed Gene Therapeutic Development for Alzheimer’s, Prion, and Parkinson’s Diseases

Maguire-Zeiss, Kathleen A., Federoff, Howard J.

Journal:

Journal of Neuroimmune Pharmacology

Year:

2009

Language:

english

File:

PDF, 296 KB

english, 2009

7

Mutant α-Synuclein Overexpression Mediates Early Proinflammatory Activity

Xiaomin Su, Howard J. Federoff, Kathleen A. Maguire-Zeiss

Journal:

Neurotoxicity Research

Year:

2009

Language:

english

File:

PDF, 615 KB

english, 2009

8

Dopamine and Paraquat Enhance α-Synuclein-Induced Alterations in Membrane Conductance

Li Rebekah Feng, Kathleen A. Maguire-Zeiss

Journal:

Neurotoxicity Research

Year:

2011

Language:

english

File:

PDF, 1.97 MB

english, 2011

9

α-Synuclein mediates alterations in membrane conductance: a potential role for α-synuclein oligomers in cell vulnerability

Li Rebekah Feng, Howard J. Federoff, Stefano Vicini, Kathleen A. Maguire-Zeiss

Journal:

European Journal of Neuroscience

Year:

2010

Language:

english

File:

PDF, 270 KB

english, 2010

10

Methamphetamine-associated cleavage of the synaptic adhesion molecule intercellular adhesion molecule-5

Katherine Conant, Irina Lonskaya, Arek Szklarczyk, Caroline Krall, Joseph Steiner, Kathleen Maguire-Zeiss, Seung T. Lim

Journal:

Journal of Neurochemistry

Year:

2011

Language:

english

File:

PDF, 578 KB

english, 2011

11

Convergent Pathobiologic Model of Parkinson's Disease

KATHLEEN A. MAGUIRE-ZEISS, HOWARD J. FEDEROFF

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 5.48 MB

2003

12

Development of Nurr1 Stable Cell Lines for the Identification of Downstream Targets

YU LUO, LEIGH A. HENRICKSEN, KATHLEEN A. MAGUIRE-ZEISS, HOWARD J. FEDEROFF

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 1.21 MB

2003

13

Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease

Lee, Byoung Dae, Shin, Joo-Ho, VanKampen, Jackalina, Petrucelli, Leonard, West, Andrew B, Ko, Han Seok, Lee, Yun-Il, Maguire-Zeiss, Kathleen A, Bowers, William J, Federoff, Howard J

Journal:

Nature Medicine

Year:

2010

Language:

english

File:

PDF, 627 KB

english, 2010

14

Effects of ex vivo transduction of mesencephalic reaggregates with bcl-2 on grafted dopamine neuron survival

Caryl E. Sortwell, William J. Bowers, Scott E. Counts, Mark R. Pitzer, Matthew F. Fleming, Susan O. McGuire, Kathleen A. Maguire-Zeiss, Howard J. Federoff, Timothy J. Collier

Journal:

Year:

2007

Language:

english

File:

PDF, 1.46 MB

english, 2007

15

Gene therapeutic approaches to the treatment of Parkinson's disease

William J. Bowers, Kathleen A. Maguire-Zeiss, Brandon K. Harvey, Howard J. Federoff

Journal:

Clinical Neuroscience Research

Year:

2001

Language:

english

File:

PDF, 166 KB

english, 2001

16

Identification of human α-synuclein specific single chain antibodies

Kathleen A. Maguire-Zeiss, Charlotte I. Wang, Eric Yehling, Mark A. Sullivan, Douglas W. Short, Xiaomin Su, Geraldine Gouzer, Leigh A. Henricksen, Charles A. Wuertzer, Howard J. Federoff

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 401 KB

english, 2006

17

Synuclein, dopamine and oxidative stress: co-conspirators in Parkinson's disease?

Kathleen A. Maguire-Zeiss, Douglas W. Short, Howard J. Federoff

Journal:

Molecular Brain Research

Year:

2005

Language:

english

File:

PDF, 111 KB

english, 2005

18

Proteomic analysis of peripheral leukocytes in Alzheimer's disease patients treated with divalproex sodium

Timothy R. Mhyre, Rebekah Loy, Pierre N. Tariot, Louis A. Profenno, Kathleen A. Maguire-Zeiss, Dabao Zhang, Paul D. Coleman, Howard J. Federoff

Journal:

Neurobiology of Aging

Year:

2008

Language:

english

File:

PDF, 736 KB

english, 2008

19

Synuclein activates microglia in a model of Parkinson's disease

Xiaomin Su, Kathleen A. Maguire-Zeiss, Rita Giuliano, Landa Prifti, Karthik Venkatesh, Howard J. Federoff

Journal:

Neurobiology of Aging

Year:

2008

Language:

english

File:

PDF, 732 KB

english, 2008

20

Somatic mosaic approaches and the aging brain

Kathleen A Maguire-Zeiss, William J Bowers, Howard J Federoff

Journal:

Neurobiology of Aging

Year:

2002

Language:

english

File:

PDF, 275 KB

english, 2002

21

P3.117 Alpha-synuclein-directed alterations in membrane electrophysiological properties: potential role for alpha-synuclein pores in cell death

L.R. Feng, K. Maguire-Zeiss

Journal:

Parkinsonism & Related Disorders

Year:

2009

Language:

english

File:

PDF, 67 KB

english, 2009

22

P3.190 The role of early oxidative stress events in Parkinson's disease

H. Hathaway, L.R. Feng, H. Federoff, T. Mhyre, K. Maguire-Zeiss

Journal:

Parkinsonism & Related Disorders

Year:

2009

Language:

english

File:

PDF, 57 KB

english, 2009

23

Misfolded α-synuclein and toll-like receptors: therapeutic targets for Parkinson's disease

Dawn Béraud, Kathleen A. Maguire-Zeiss

Journal:

Parkinsonism & Related Disorders

Year:

2012

Language:

english

File:

PDF, 354 KB

english, 2012

24

1.2.3 MISFOLDED α-SYNUCLEIN AND NEUROINFLAMMATION AS THERAPEUTIC TARGETS FOR PARKINSON'S DISEASE

K.A. Maguire-Zeiss

Journal:

Parkinsonism & Related Disorders

Year:

2012

Language:

english

File:

PDF, 55 KB

english, 2012

25

Human Interleukin-10 Gene Transfer Is Protective in a Rat Model of Parkinson's Disease

Johnston, Louisa C, Su, Xiaomin, Maguire-Zeiss, Kathleen, Horovitz, Karen, Ankoudinova, Irina, Guschin, Dmitry, Hadaczek, Piotr, Federoff, Howard J, Bankiewicz, Krystof, Forsayeth, John

Journal:

Molecular Therapy

Year:

2008

Language:

english

File:

PDF, 397 KB

english, 2008

26

α-Synuclein: A therapeutic target for Parkinson’s disease?

Kathleen A. Maguire-Zeiss

Journal:

Pharmacological Research

Year:

2008

Language:

english

File:

PDF, 111 KB

english, 2008

27

Introduction

K. Maguire-Zeiss

Journal:

Neurotoxicity Research

Year:

2013

Language:

english

File:

PDF, 71 KB

english, 2013

28

Development of Inducible Leucine-rich Repeat Kinase 2 (LRRK2) Cell Lines for Therapeutics Development in Parkinson’s Disease

Huang, Liang, Shimoji, Mika, Wang, Juan, Shah, Salim, Kamila, Sukanta, Biehl, Edward R., Lim, Seung, Chang, Allison, Maguire-Zeiss, Kathleen A., Su, Xiaomin, Federoff, Howard J.

Journal:

Neurotherapeutics

Year:

2013

Language:

english

File:

PDF, 703 KB

english, 2013

29

The beneficial effect of a prolyl oligopeptidase inhibitor, KYP-2047, on alpha-synuclein clearance and autophagy in A30P transgenic mouse

Savolainen, Mari H., Richie, Christopher T., Harvey, Brandon K., Männistö, Pekka T., Maguire-Zeiss, Kathleen A., Myöhänen, Timo T.

Journal:

Neurobiology of Disease

Year:

2014

Language:

english

File:

PDF, 2.84 MB

english, 2014

30

P3-259 Expression of pathogenic tau, P301L, leads to microtubule disruption in hippocampal neurons

Callahan, Linda M., Edwards, Kenessa, Maguire-Zeiss, Kathy A., Bowers, William J., Narrow, Wade C., Kang, Susan, Mastrangelo, Michael A., Giuliano, Rita E., Federoff, Howard J.

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 169 KB

english, 2004

31

Gene Therapy in Parkinson’s Disease

Li Rebekah Feng,Dr Kathleen A. Maguire-Zeiss

Journal:

Year:

2010

Language:

english

File:

PDF, 194 KB

english, 2010

32

Activation of MyD88-dependent TLR1/2 signaling by misfolded -synuclein, a protein linked to neurodegenerative disorders

Daniele, S. G., Beraud, D., Davenport, C., Cheng, K., Yin, H., Maguire-Zeiss, K. A.

Journal:

Science Signaling

Year:

2015

Language:

english

File:

PDF, 935 KB

english, 2015

33

Isolation of Cortical Microglia with Preserved Immunophenotype and Functionality From Murine Neonates

Daniele, Stefano G., Edwards, Amanda A., Maguire-Zeiss, Kathleen A.

Journal:

Journal of Visualized Experiments

Year:

2014

Language:

english

File:

PDF, 283 KB

english, 2014

34

In Situ Hybridization in Neurobiology: Advances in Methodology

Maguire-Zeiss, K. A.

Journal:

Archives of Neurology

Year:

1995

Language:

english

File:

PDF, 128 KB

english, 1995

35

Matrix Metalloproteinase Dependent Cleavage of Cell Adhesion Molecules in the Pathogenesis of CNS Dysfunction with HIV and Methamphetamine

Conant, Katherine, T. Lim, Seung, Randall, Brad, A. Maguire-Zeiss, Kathleen

Journal:

Current HIV Research

Year:

2012

Language:

english

File:

PDF, 284 KB

english, 2012

36

Potential of Nurr1 interactions to disclose new Parkinson’s therapeutics

Federoff, Howard J, Brown, Milton, Dakshanamurthy, Sivanesan, Maguire-Zeiss, Kathleen

Journal:

Future Neurology

Year:

2009

Language:

english

File:

PDF, 618 KB

english, 2009

37

PREFERENTIAL LOSS OF PREPROENKEPHALIN VERSUS PREPROTACHYKININ STRIATAL NEURONS FROM HUNTINGTONʼS DISEASE PATIENTS

Richfield, E. K., Maguire-Zeiss, K. A., Vonkemann, H. E., Voorn, P.

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

1995

File:

PDF, 118 KB

1995

38

Inflammation alters AMPA-stimulated calcium responses in dorsal striatal D2 but not D1 spiny projection neurons

Winland, Carissa D., Welsh, Nora, Sepulveda-Rodriguez, Alberto, Vicini, Stefano, Maguire-Zeiss, Kathleen A.

Journal:

European Journal of Neuroscience

Year:

2017

Language:

english

File:

PDF, 1.43 MB

english, 2017

39

α-Synuclein Alters Toll-Like Receptor Expression

Béraud, Dawn, Twomey, Margaret, Bloom, Benjamin, Mittereder, Andrew, Ton, Vy, Neitzke, Katherine, Chasovskikh, Sergey, Mhyre, Timothy R., Maguire-Zeiss, Kathleen A.

Journal:

Frontiers in Neuroscience

Year:

2011

Language:

english

File:

PDF, 1.02 MB

english, 2011

40

Toll-Like Receptor 2 Signaling and Current Approaches for Therapeutic Modulation in Synucleinopathies

Caplan, Ian F., Maguire-Zeiss, Kathleen A.

Journal:

Frontiers in Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.50 MB

english, 2018

41

From student to steward: the Interdisciplinary Program in Neuroscience at Georgetown University as a case study in professional development during doctoral training

Ullrich, Lauren, Dumanis, Sonya B., Evans, Tanya M., Jeannotte, Alexis M., Leonard, Carrie, Rozzi, Summer J., Taylor, Caitlin M., Gale, Karen, Kanwal, Jagmeet S., Maguire-Zeiss, Kathleen A., Wolfe, Ba

Journal:

Medical Education Online

Year:

2014

Language:

english

File:

PDF, 838 KB

english, 2014

42

4395 alpha-Synuclein Induced Reactive Gliosis

Carey, Sean David, Alshawi, Sarah, McCann, Mondona, Maguire-Zeiss, Kathleen

Journal:

Journal of Clinical and Translational Science

Year:

2020

File:

PDF, 59 KB

2020

43

MMP13 Expression Is Increased Following Mutant Î±-Synuclein Exposure and Promotes Inflammatory Responses in Microglia

SÃ¡nchez, Kathryn, Maguire-Zeiss, Kathleen

Journal:

Frontiers in Neuroscience

Year:

2020

File:

PDF, 1.63 MB

2020

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